Reactome | Insertion of tail-anchored proteins into the endoplasmic reticulum membrane

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Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Show undefined attributes

created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11050832
displayName	Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
eventOf	[TopLevelPathway:R-DDI-9609507] Protein localization - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:18899] protein insertion into ER membrane
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-DDI-9609921] SGTA binds Tail-anchored protein - Dictyostelium discoideum [Reaction:R-DDI-9617595] SGTA binds mislocalized membrane protein - Dictyostelium discoideum
inferredFrom	[Pathway:R-HSA-9609523] Insertion of tail-anchored proteins into the endoplasmic reticulum membrane - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-9609523
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[TopLevelPathway:R-DDI-9609507] Protein localization
(inferredTo)	[Pathway:R-HSA-9609523] Insertion of tail-anchored proteins into the endoplasmic reticulum membrane

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