Reactome | Association of p-S216-CDC25C with 14-3-3 proteins

Schema > Reaction > Entries

Association of p-S216-CDC25C with 14-3-3 proteins Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11001187
displayName	Association of p-S216-CDC25C with 14-3-3 proteins
eventOf	[Pathway:R-DDI-5625740] RHO GTPases activate PKNs - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-75016] Association of p-S216-CDC25C with 14-3-3 proteins - Homo sapiens
input	[EntityWithAccessionedSequence:R-DDI-75003] phospho-cdc25 [cytosol] [Complex:R-DDI-194364] YWHAE dimer [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Association of p-S216-CDC25C with 14-3-3 proteins
output	[Complex:R-DDI-75005] p-S216-CDC25C:14-3-3 protein complex [cytosol]
precedingEvent	[BlackBoxEvent:R-DDI-9029987] p-S216-CDC25C translocates to the cytosol - Dictyostelium discoideum [Reaction:R-DDI-5671749] p-T774-PKN1 phosphorylates CDC25C - Dictyostelium discoideum
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-75016
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DDI-5625740] RHO GTPases activate PKNs [Pathway:R-DDI-75035] Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
(inferredTo)	[Reaction:R-HSA-75016] Association of p-S216-CDC25C with 14-3-3 proteins

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