Reactome | Inflammasomes

Schema > Pathway > Entries

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11050070
displayName	Inflammasomes
eventOf	[Pathway:R-DDI-168643] Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-DDI-844456] The NLRP3 inflammasome - Dictyostelium discoideum
inferredFrom	[Pathway:R-HSA-622312] Inflammasomes - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Inflammasomes
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-622312
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DDI-168643] Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
(inferredTo)	[Pathway:R-HSA-622312] Inflammasomes