Reactome | FUCA1 hydrolyses NGP:1,6-GlcNAc

Schema > Reaction > Entries

FUCA1 hydrolyses NGP:1,6-GlcNAc Show undefined attributes

catalystActivity	[CatalystActivity:11029975] alpha-L-fucosidase activity of FUCA1 tetramer [lysosomal lumen]
category	transition
compartment	[Compartment:161320] lysosomal lumen
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11029977
displayName	FUCA1 hydrolyses NGP:1,6-GlcNAc
eventOf	[Pathway:R-DDI-975578] Reactions specific to the complex N-glycan synthesis pathway - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5693807] FUCA1 hydrolyses NGP:1,6-GlcNAc - Homo sapiens
input	[SimpleEntity:R-ALL-1605715] H2O [lysosomal lumen] [OtherEntity:R-ALL-6784247] NGP:1,6-GlcNAc [lysosomal lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	FUCA1 hydrolyses NGP:1,6-GlcNAc
output	[SimpleEntity:R-ALL-6784249] L-fucose [lysosomal lumen] [SimpleEntity:R-ALL-6784248] NGP [lysosomal lumen]
precedingEvent	[Reaction:R-DDI-1028788] FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP - Dictyostelium discoideum
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-5693807
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DDI-975578] Reactions specific to the complex N-glycan synthesis pathway
(inferredTo)	[Reaction:R-HSA-5693807] FUCA1 hydrolyses NGP:1,6-GlcNAc