Reactome | CUL1, SKP1, FBXL5 bind

Schema > Reaction > Entries

CUL1, SKP1, FBXL5 bind Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11029676
displayName	CUL1, SKP1, FBXL5 bind
eventOf	[Pathway:R-DDI-917937] Iron uptake and transport - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DDI-5691176] NEDD8 binds CUL1 (in SKP1:CUL1:FXBL5) - Dictyostelium discoideum
inferredFrom	[Reaction:R-HSA-5691167] CUL1, SKP1, FBXL5 bind - Homo sapiens
input	[EntityWithAccessionedSequence:R-DDI-391295] FBXL5 [cytosol] [DefinedSet:R-DDI-174230-4] Homologues of CUL1 [cytosol] [DefinedSet:R-DDI-174150-3] Homologues of SKP1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	CUL1, SKP1, FBXL5 bind
output	[Complex:R-DDI-5691178] SKP1:CUL1:FBXL5 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-5691167
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DDI-917937] Iron uptake and transport
(precedingEvent)	[Reaction:R-DDI-5691176] NEDD8 binds CUL1 (in SKP1:CUL1:FXBL5)
(inferredTo)	[Reaction:R-HSA-5691167] CUL1, SKP1, FBXL5 bind