Reactome | rnf160 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

candidateOf	[CandidateSet:R-DDI-976075] E3 ligases in proteasomal degradation [cytosol] - Dictyostelium discoideum
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-DDI-9948361] LTN1:TCF25:NEMF:60S ribosomal subunit:peptidyl-tRNA with K48polyUb-nascent peptide-Ala [cytosol] - Dictyostelium discoideum [Complex:R-DDI-9948416] VCP hexamer:UFD1:NPLOC4:LTN1:NEMF:TCF25:60S ribosome subunit:peptidyl-tRNA with K48polyUb-nascent peptide-Ala [cytosol] - Dictyostelium discoideum
consumedByEvent	[Reaction:R-DDI-9948318] LTN1 and TCF25 bind NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide-Ala - Dictyostelium discoideum
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11014838
displayName	rnf160 [cytosol]
endCoordinate	1766
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-5688967] LTN1 [cytosol] - Homo sapiens
maxDepth	1
name	rnf160 LTN1 Q555H8
referenceEntity	[ReferenceGeneProduct:uniprot:Q555H8] UniProt:Q555H8
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-5688967
startCoordinate	1

(activeUnit)	[CatalystActivity:11048594] ubiquitin protein ligase activity of LTN1:TCF25:NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide-Ala [cytosol]
(hasComponent)	[Complex:R-DDI-9948416] VCP hexamer:UFD1:NPLOC4:LTN1:NEMF:TCF25:60S ribosome subunit:peptidyl-tRNA with K48polyUb-nascent peptide-Ala [cytosol] [Complex:R-DDI-9948361] LTN1:TCF25:NEMF:60S ribosomal subunit:peptidyl-tRNA with K48polyUb-nascent peptide-Ala [cytosol] [Complex:R-DDI-9948455] LTN1:TCF25:NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide-Ala [cytosol]
(input)	[Reaction:R-DDI-9948318] LTN1 and TCF25 bind NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide-Ala
(hasCandidate)	[CandidateSet:R-DDI-976075] E3 ligases in proteasomal degradation [cytosol]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-5688967] LTN1 [cytosol]