Reactome | p-T2609,S2612,T2638,T2647-PRKDC:XRCC5:XRCC6:p-S516,S645-DCLRE1C:XRCC4:LIG4:NHEJ1:POLL,POLM:Extended ligatable DNA DSB ends [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11028067
displayName	p-T2609,S2612,T2638,T2647-PRKDC:XRCC5:XRCC6:p-S516,S645-DCLRE1C:XRCC4:LIG4:NHEJ1:POLL,POLM:Extended ligatable DNA DSB ends [nucleoplasm]
hasComponent	[OtherEntity:R-ALL-5687361] Extended ligatable DNA DSB ends [nucleoplasm] [GenomeEncodedEntity:R-DDI-5687176] Ghost homologue of p-S516,S645-DCLRE1C [nucleoplasm] [GenomeEncodedEntity:R-DDI-5687355] Ghost homologue of POLL,POLM [nucleoplasm] [Complex:R-DDI-5687234] NHEJ1 [nucleoplasm] 2 × [Complex:R-DDI-5687152] p-T2609,S2612,T2638,T2647-PRKDC:XRCC5:XRCC6 heterotrimer [nucleoplasm] [Complex:R-DDI-75912] XRCC4:LIG4 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-5687362] p-T2609,S2612,T2638,T2647-PRKDC:XRCC5:XRCC6:p-S516,S645-DCLRE1C:XRCC4:LIG4:NHEJ1:POLL,POLM:Extended ligatable DNA DSB ends [nucleoplasm] - Homo sapiens
maxDepth	4
name	p-T2609,S2612,T2638,T2647-PRKDC:XRCC5:XRCC6:p-S516,S645-DCLRE1C:XRCC4:LIG4:NHEJ1:POLL,POLM:Extended ligatable DNA DSB ends
producedByEvent	[Reaction:R-DDI-5687360] POLL or POLM extends aligned DNA DSB ends to fill gaps - Dictyostelium discoideum
schemaClass	Complex
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-5687362
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(inferredTo)	[Complex:R-HSA-5687362] p-T2609,S2612,T2638,T2647-PRKDC:XRCC5:XRCC6:p-S516,S645-DCLRE1C:XRCC4:LIG4:NHEJ1:POLL,POLM:Extended ligatable DNA DSB ends [nucleoplasm]
(output)	[Reaction:R-DDI-5687360] POLL or POLM extends aligned DNA DSB ends to fill gaps

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