Reactome | Signaling by Hedgehog

Schema > Pathway > Entries

created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11050454
displayName	Signaling by Hedgehog
eventOf	[TopLevelPathway:R-DDI-162582] Signal Transduction - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-DDI-5358346] Hedgehog ligand biogenesis - Dictyostelium discoideum [Pathway:R-DDI-5610787] Hedgehog 'off' state - Dictyostelium discoideum [Pathway:R-DDI-5632684] Hedgehog 'on' state - Dictyostelium discoideum
inferredFrom	[Pathway:R-HSA-5358351] Signaling by Hedgehog - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Signaling by Hedgehog
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-5358351
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[TopLevelPathway:R-DDI-162582] Signal Transduction
(inferredTo)	[Pathway:R-HSA-5358351] Signaling by Hedgehog