Reactome | pyrophosphate + H2O => 2 orthophosphate [mitochondrial]

Schema > Reaction > Entries

pyrophosphate + H2O => 2 orthophosphate [mitochondrial] Show undefined attributes

catalystActivity	[CatalystActivity:11012200] inorganic diphosphate phosphatase activity of PPA2 dimer [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11012202
displayName	pyrophosphate + H2O => 2 orthophosphate [mitochondrial]
eventOf	[Pathway:R-DDI-379726] Mitochondrial tRNA aminoacylation - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-449937] pyrophosphate + H2O => 2 orthophosphate [mitochondrial] - Homo sapiens
input	[SimpleEntity:R-ALL-113521] H2O [mitochondrial matrix] [SimpleEntity:R-ALL-159450] PPi [mitochondrial matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	pyrophosphate + H2O => 2 orthophosphate [mitochondrial]
output	2 × [SimpleEntity:R-ALL-113548] Pi [mitochondrial matrix]
regulatedBy	[Requirement:R-GGA-354222] Requirement by 'Mg2+ [mitochondrial matrix]'
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-449937
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DDI-379726] Mitochondrial tRNA aminoacylation [Pathway:R-DDI-71737] Pyrophosphate hydrolysis
(inferredTo)	[Reaction:R-HSA-449937] pyrophosphate + H2O => 2 orthophosphate [mitochondrial]

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