Reactome | HDACs deacetylate histones

Schema > Pathway > Entries

created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11050412
displayName	HDACs deacetylate histones
eventOf	[Pathway:R-DDI-3247509] Chromatin modifying enzymes - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DDI-3782637] HDAC8 deacetylates histones - Dictyostelium discoideum [Reaction:R-DDI-3782655] HDAC10 deacetylates histone - Dictyostelium discoideum
inferredFrom	[Pathway:R-HSA-3214815] HDACs deacetylate histones - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	HDACs deacetylate histones
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-3214815
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DDI-3247509] Chromatin modifying enzymes
(inferredTo)	[Pathway:R-HSA-3214815] HDACs deacetylate histones

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