Reactome | Establishment of Sister Chromatid Cohesion

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Establishment of Sister Chromatid Cohesion Show undefined attributes

compartment	[Compartment:1598585] chromosome [Compartment:81347] chromosome, centromeric region [Compartment:7660] nucleoplasm
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11050332
displayName	Establishment of Sister Chromatid Cohesion
eventOf	[Pathway:R-DDI-69242] S Phase - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:18485] sister chromatid cohesion
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DDI-2468039] Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 - Dictyostelium discoideum [Reaction:R-DDI-2473152] Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 - Dictyostelium discoideum
inferredFrom	[Pathway:R-HSA-2468052] Establishment of Sister Chromatid Cohesion - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Establishment of Sister Chromatid Cohesion
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-2468052
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DDI-69242] S Phase
(inferredTo)	[Pathway:R-HSA-2468052] Establishment of Sister Chromatid Cohesion

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