Reactome | NOSIP mediated eNOS trafficking

Schema > Pathway > Entries

created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11049730
displayName	NOSIP mediated eNOS trafficking
eventOf	[Pathway:R-DDI-202131] Metabolism of nitric oxide: NOS3 activation and regulation - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:18827] nitric oxide metabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DDI-203553] eNOS binds NOSIP - Dictyostelium discoideum [Reaction:R-DDI-203680] eNOS:NOSIP translocation from caveolae to intracellular compartments - Dictyostelium discoideum
inferredFrom	[Pathway:R-HSA-203754] NOSIP mediated eNOS trafficking - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	NOSIP mediated eNOS trafficking
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-203754
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DDI-202131] Metabolism of nitric oxide: NOS3 activation and regulation
(inferredTo)	[Pathway:R-HSA-203754] NOSIP mediated eNOS trafficking

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