Reactome | Vitamin D (calciferol) metabolism

Schema > Pathway > Entries

created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11049768
displayName	Vitamin D (calciferol) metabolism
eventOf	[Pathway:R-DDI-8957322] Metabolism of steroids - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:11287] vitamin D metabolic process
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-DDI-209845] CYP2R1 25-hydroxylates VD3 to 25(OH)D - Dictyostelium discoideum
inferredFrom	[Pathway:R-HSA-196791] Vitamin D (calciferol) metabolism - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Vitamin D (calciferol) metabolism
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-196791
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DDI-8957322] Metabolism of steroids
(hasEncapsulatedEvent)	[Pathway:R-DDI-5652084] Fructose metabolism [Pathway:R-DDI-191273] Cholesterol biosynthesis
(inferredTo)	[Pathway:R-HSA-196791] Vitamin D (calciferol) metabolism

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