Reactome | Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160)

Schema > Reaction > Entries

Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) Show undefined attributes

catalystActivity	[CatalystActivity:11005091] cyclin-dependent protein serine/threonine kinase activity of CCNA:p-T160-CDK2:E2F1/E2F3 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11005093
displayName	Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160)
eventOf	[Pathway:R-DDI-68911] G2 Phase - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-187959] Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) - Homo sapiens
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [Complex:R-DDI-187932] CCNA:p-T160-CDK2:E2F1/E2F3 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160)
output	[SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [Complex:R-DDI-187944] CCNA:p-T160-CDK2:p-E2F1/p-E2F3 [nucleoplasm]
precedingEvent	[Reaction:R-DDI-187937] Association of Cyclin A:phospho-Cdk2(Thr 160) with E2F1/E2F3 - Dictyostelium discoideum
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-187959
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DDI-68911] G2 Phase
(inferredTo)	[Reaction:R-HSA-187959] Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160)

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