Reactome | Translocation of Cyclin A:Cdk2 complexes to the nucleus

Schema > Reaction > Entries

Translocation of Cyclin A:Cdk2 complexes to the nucleus Show undefined attributes

category	transition
compartment	[Compartment:13231] nuclear envelope
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11004762
displayName	Translocation of Cyclin A:Cdk2 complexes to the nucleus
eventOf	[Pathway:R-DDI-69656] Cyclin A:Cdk2-associated events at S phase entry - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DDI-174164] Phosphorylation of Cyclin A:Cdk2 at Tyr 15 - Dictyostelium discoideum [Reaction:R-DDI-187949] CAK-mediated phosphorylation of Cyclin A:Cdk2 - Dictyostelium discoideum
inferredFrom	[Reaction:R-HSA-174273] Translocation of Cyclin A:Cdk2 complexes to the nucleus - Homo sapiens
input	[Complex:R-DDI-187501] CCNA:CDK2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Translocation of Cyclin A:Cdk2 complexes to the nucleus
output	[Complex:R-DDI-141608] CCNA:CDK2 [nucleoplasm]
precedingEvent	[Reaction:R-DDI-174054] Formation of Cyclin A:Cdk2 complexes - Dictyostelium discoideum
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-174273
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DDI-69656] Cyclin A:Cdk2-associated events at S phase entry
(precedingEvent)	[Reaction:R-DDI-187949] CAK-mediated phosphorylation of Cyclin A:Cdk2 [Reaction:R-DDI-174164] Phosphorylation of Cyclin A:Cdk2 at Tyr 15
(inferredTo)	[Reaction:R-HSA-174273] Translocation of Cyclin A:Cdk2 complexes to the nucleus

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