Reactome | FXN:NFS1:ISD11:ISCU:2Fe-2S Cluster [mitochondrial matrix]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:11047869] iron chaperone activity of FXN:NFS1:ISD11:ISCU:2Fe-2S Cluster [mitochondrial matrix]
compartment	[Compartment:5460] mitochondrial matrix
consumedByEvent	[Reaction:R-DDI-9866272] 2Fe-2S is inserted in UQCRFS1 - Dictyostelium discoideum
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11016022
displayName	FXN:NFS1:ISD11:ISCU:2Fe-2S Cluster [mitochondrial matrix]
hasComponent	2 × [SimpleEntity:R-ALL-1362383] 2Fe-2S cluster [mitochondrial matrix] 2 × [EntityWithAccessionedSequence:R-DDI-1362390] fxn [mitochondrial matrix] 2 × [EntityWithAccessionedSequence:R-DDI-1362391] ISCU-1 [mitochondrial matrix] 2 × [EntityWithAccessionedSequence:R-DDI-1362392] lyrm4 [mitochondrial matrix] 2 × [EntityWithAccessionedSequence:R-DDI-1362396] PXLP-K258-NFS1-1 [mitochondrial matrix]
inDisease	false
inferredFrom	[Complex:R-HSA-1362398] FXN:NFS1:ISD11:ISCU:2Fe-2S Cluster [mitochondrial matrix] - Homo sapiens
maxDepth	2
name	FXN:NFS1:ISD11:ISCU:2Fe-2S Cluster
producedByEvent	[BlackBoxEvent:R-DDI-1362408] FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster - Dictyostelium discoideum
schemaClass	Complex
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-1362398
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-DDI-9866272] 2Fe-2S is inserted in UQCRFS1
(physicalEntity)	[CatalystActivity:11047869] iron chaperone activity of FXN:NFS1:ISD11:ISCU:2Fe-2S Cluster [mitochondrial matrix]
(output)	[BlackBoxEvent:R-DDI-1362408] FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster
(inferredTo)	[Complex:R-HSA-1362398] FXN:NFS1:ISD11:ISCU:2Fe-2S Cluster [mitochondrial matrix]

Cite Us!