Reactome | Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2

Schema > Reaction > Entries

Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2 Show undefined attributes

category	dissociation
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11002129
displayName	Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2
eventOf	[Pathway:R-DDI-112411] MAPK1 (ERK2) activation - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DDI-5674385] p-T,Y MAPKs dimerize - Dictyostelium discoideum
inferredFrom	[Reaction:R-HSA-109864] Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2 - Homo sapiens
input	[Complex:R-DDI-109854] p-S,T-MAP2K2:p-T,Y-MAPK1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2
output	[EntityWithAccessionedSequence:R-DDI-109848] phospho-p-S,T-MAP2K2 [cytosol] [EntityWithAccessionedSequence:R-DDI-109853] phospho-p-T185,Y187-MAPK1 [cytosol]
precedingEvent	[Reaction:R-DDI-109862] MAP2K2 phosphorylates MAPK1 - Dictyostelium discoideum
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-109864
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DDI-112411] MAPK1 (ERK2) activation
(precedingEvent)	[Reaction:R-DDI-5674385] p-T,Y MAPKs dimerize
(inferredTo)	[Reaction:R-HSA-109864] Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2

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