Reactome | nsp10:nsp14 [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-COV-9815359] ExoN inhibitors:nsp10:nsp14 [cytosol] - Severe acute respiratory syndrome coronavirus 2
consumedByEvent	[Reaction:R-HSA-9731708] nsp10:nsp14 binds to ExoN inhibitors - Homo sapiens [Reaction:R-HSA-9694304] nsp14 binds nsp12 - Homo sapiens
created	[InstanceEdit:9694660] Cook, Justin, 2020-07-07
crossReference	[DatabaseIdentifier:12020746] Mondo:0100096
dbId	9694688
disease	[Disease:9683912] COVID-19
displayName	nsp10:nsp14 [cytosol]
hasComponent	[DefinedSet:R-COV-9694358] nsp10 [cytosol] [EntityWithAccessionedSequence:R-COV-9694537] pp1ab-nsp14 [cytosol]
inDisease	true
inferredFrom	[Complex:R-COV-9682545] nsp10:nsp14 [cytosol] - Human SARS coronavirus
isChimeric	false
maxDepth	3
modified	[InstanceEdit:9751171] Matthews, Lisa, 2021-08-18
name	nsp10:nsp14
producedByEvent	[Reaction:R-HSA-9694542] nsp14 binds nsp10 - Homo sapiens
schemaClass	Complex
species	[Species:9681683] Severe acute respiratory syndrome coronavirus 2
stId	R-COV-9694688
summation	[Summation:9694775] This COVID-19 Complex instance was generated via electronic inference from a curated CoV-1 (Human SARS coronavirus) Reactome instance. In Reactome, inference is the process used to automatically create orthologous Pathways, Reactions and PhysicalEntities from our expertly curated data (https://reactome.org/documentation/inferred-events).

(hasComponent)	[Complex:R-COV-9815359] ExoN inhibitors:nsp10:nsp14 [cytosol] [Complex:R-COV-9694597] nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol]
(input)	[Reaction:R-HSA-9731708] nsp10:nsp14 binds to ExoN inhibitors [Reaction:R-HSA-9694304] nsp14 binds nsp12
(output)	[Reaction:R-HSA-9694542] nsp14 binds nsp10
(inferredTo)	[Complex:R-COV-9682545] nsp10:nsp14 [cytosol]