Reactome | AADAT transaminates 3HKYN to xanthurenate

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AADAT transaminates 3HKYN to xanthurenate Show undefined attributes

catalystActivity	[CatalystActivity:10328492] transaminase activity of AADAT dimer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10328494
displayName	AADAT transaminates 3HKYN to xanthurenate
eventOf	[Pathway:R-CFA-71240] Tryptophan catabolism - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9972889] AADAT transaminates 3HKYN to xanthurenate - Homo sapiens
input	[SimpleEntity:R-ALL-34351] 3HKYN [cytosol] [SimpleEntity:R-ALL-5367039] glyoxylate [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	AADAT transaminates 3HKYN to xanthurenate 3-hydroxy-L-kynurenine + glyoxylate => xanthurenate + glycine + H2O
output	[SimpleEntity:R-ALL-29424] Gly [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-9972885] xanthurenate [cytosol]
precedingEvent	[Reaction:R-CFA-71200] kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-9972889
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-71240] Tryptophan catabolism
(inferredTo)	[Reaction:R-HSA-9972889] AADAT transaminates 3HKYN to xanthurenate

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