Reactome | AAC1 imports a proton

Schema > Reaction > Entries

AAC1 imports a proton Show undefined attributes

catalystActivity	[CatalystActivity:10325986] proton transmembrane transporter activity of AAC1 [mitochondrial inner membrane]
category	transition
compartment	[Compartment:17927] mitochondrial intermembrane space [Compartment:5460] mitochondrial matrix
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10325988
displayName	AAC1 imports a proton
eventOf	[Pathway:R-CFA-166187] Mitochondrial Uncoupling - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9864415] AAC1 imports a proton - Homo sapiens
input	[SimpleEntity:R-ALL-163953] H+ [mitochondrial intermembrane space]
isInDisease	false
isInferred	true
maxDepth	1
name	AAC1 imports a proton
output	[SimpleEntity:R-ALL-113529] H+ [mitochondrial matrix]
precedingEvent	[Reaction:R-CFA-163217] Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 - Canis familiaris [Reaction:R-CFA-163214] Electron transfer from reduced cytochrome c to molecular oxygen - Canis familiaris
regulatedBy	[Requirement:9997150] Requirement by 'LCFA(-) [mitochondrial inner membrane]' [NegativeRegulation:R-HSA-70334] Negative regulation by 'ADP [cytosol]'
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-9864415
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-166187] Mitochondrial Uncoupling
(inferredTo)	[Reaction:R-HSA-9864415] AAC1 imports a proton