Reactome | N4BP1 binds IKBKG

Schema > Reaction > Entries

N4BP1 binds IKBKG Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10322296
displayName	N4BP1 binds IKBKG
eventOf	[Pathway:R-CFA-9758274] Regulation of NF-kappa B signaling - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:162165] negative regulation of canonical NF-kappaB signal transduction
inferredFrom	[Reaction:R-HSA-9757954] N4BP1 binds IKBKG - Homo sapiens
input	[EntityWithAccessionedSequence:R-CFA-168108] IKBKG [cytosol] [EntityWithAccessionedSequence:R-CFA-9757941] N4BP1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	N4BP1 binds IKBKG
output	[Complex:R-CFA-9757950] IKBKG:N4BP1 [cytosol]
regulatedBy	[NegativeRegulation:10322297] Negative regulation by 'active caspase-8 [cytosol]'
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-9757954
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-9758274] Regulation of NF-kappa B signaling
(inferredTo)	[Reaction:R-HSA-9757954] N4BP1 binds IKBKG