Reactome | p-VAV1,2,3 exchange 6TGTP for GDP on RAC1

Schema > Reaction > Entries

p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 Show undefined attributes

catalystActivity	[CatalystActivity:10322132] guanyl-nucleotide exchange factor activity of p-VAV family [cytosol]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10322134
displayName	p-VAV1,2,3 exchange 6TGTP for GDP on RAC1
eventOf	[Pathway:R-CFA-9748787] Azathioprine ADME - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:528650] cellular response to xenobiotic stimulus
inferredFrom	[Reaction:R-HSA-9751201] p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 - Homo sapiens
input	[SimpleEntity:R-ALL-9748947] 6TGTP [cytosol] [Complex:R-CFA-5674631] RAC1:GDP [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	p-VAV1,2,3 exchange 6TGTP for GDP on RAC1
output	[SimpleEntity:R-ALL-29420] GDP [cytosol] [Complex:R-CFA-5674631] RAC1:GDP [plasma membrane]
precedingEvent	[Reaction:R-CFA-9748999] NME1:2 hexamer phosphorylates 6TGDP to 6TGTP - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-9751201
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-9748787] Azathioprine ADME
(inferredTo)	[Reaction:R-HSA-9751201] p-VAV1,2,3 exchange 6TGTP for GDP on RAC1

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