Reactome | AR binds AR antagonists

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10320927
displayName	AR binds AR antagonists
eventOf	[Pathway:R-CFA-3371497] HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9706837] AR binds AR antagonists - Homo sapiens
input	[DefinedSet:R-ALL-9706850] AR antagonists [cytosol] [Complex:R-CFA-9705922] HSP90:ATP:FKBP4:PTGES3:AR [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	AR binds AR antagonists
output	[Complex:R-CFA-9706851] HSP90:ATP:FKBP4:PTGES3:AR:AR antagonists [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-9706837
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-3371497] HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
(inferredTo)	[Reaction:R-HSA-9706837] AR binds AR antagonists