Reactome | ESR1 binds to TFF1 gene promoter

Schema > Reaction > Entries

ESR1 binds to TFF1 gene promoter Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10316251
displayName	ESR1 binds to TFF1 gene promoter
eventOf	[Pathway:R-CFA-9018519] Estrogen-dependent gene expression - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-9009536] DDX5 binds ESR1:estrogen:TFF1 gene promoter - Canis familiaris
inferredFrom	[Reaction:R-HSA-9009541] ESR1 binds to TFF1 gene promoter - Homo sapiens
input	[Complex:R-CFA-9008284] ESR1 dimer:estrogen [nucleoplasm] [Complex:R-CFA-9023820] TFF1 gene:FOXA1:GATA3 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	ESR1 binds to TFF1 gene promoter
output	[Complex:R-CFA-9009531] ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-9009541
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-9018519] Estrogen-dependent gene expression
(precedingEvent)	[Reaction:R-CFA-9009536] DDX5 binds ESR1:estrogen:TFF1 gene promoter
(inferredTo)	[Reaction:R-HSA-9009541] ESR1 binds to TFF1 gene promoter

Cite Us!