Reactome | TBK1 phosphorylation

Schema > BlackBoxEvent > Entries

TBK1 phosphorylation Show undefined attributes

category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10316131
displayName	TBK1 phosphorylation
eventOf	[Pathway:R-CFA-9008059] Interleukin-37 signaling - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-9008684] TBK1 phosphorylation - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [EntityWithAccessionedSequence:R-CFA-166267] TBK1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	TBK1 phosphorylation
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [EntityWithAccessionedSequence:R-CFA-9008705] phospho-TBK1 [cytosol]
precedingEvent	[Reaction:R-CFA-9008577] IL37:IL18R1 binds SIGIRR - Canis familiaris
regulatedBy	[NegativeRegulation:10316132] Negative regulation by 'IL18R1:IL37,IL37(?-218):SIGIRR [plasma membrane]'
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:49646] Canis familiaris
stId	R-CFA-9008684
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-9008059] Interleukin-37 signaling
(inferredTo)	[BlackBoxEvent:R-HSA-9008684] TBK1 phosphorylation