Reactome | 26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates

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26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates Show undefined attributes

category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10314872
displayName	26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates
eventOf	[Pathway:R-CFA-8951664] Neddylation - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-8956184] 26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates - Homo sapiens
input	[Complex:R-CFA-8956137] NEDD8,UBD:NUB1:26S proteasome [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates
output	[Complex:R-CFA-68819] 26S proteasome [cytosol] [EntityWithAccessionedSequence:R-CFA-8956129] NUB1 [cytosol]
precedingEvent	[Reaction:R-CFA-8956140] NEDD8 and UBD bind NUB1 and the 26S proteasome - Canis familiaris
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:49646] Canis familiaris
stId	R-CFA-8956184
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-8951664] Neddylation
(inferredTo)	[BlackBoxEvent:R-HSA-8956184] 26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates

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