Reactome | NEDD8:AcM-UBE2M binds CUL9:RBX1 ubiquitin ligase complex

Schema > Reaction > Entries

NEDD8:AcM-UBE2M binds CUL9:RBX1 ubiquitin ligase complex Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10314824
displayName	NEDD8:AcM-UBE2M binds CUL9:RBX1 ubiquitin ligase complex
eventOf	[Pathway:R-CFA-8951664] Neddylation - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-8956025] AcM-UBE2M transfers NEDD8 to CUL9:RBX1 - Canis familiaris
inferredFrom	[Reaction:R-HSA-8956031] NEDD8:AcM-UBE2M binds CUL9:RBX1 ubiquitin ligase complex - Homo sapiens
input	[Complex:R-CFA-8855013] CUL9:RBX1 [cytosol] [Complex:R-CFA-4419896] NEDD8-AcM-UBE2M [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	NEDD8:AcM-UBE2M binds CUL9:RBX1 ubiquitin ligase complex
output	[Complex:R-CFA-8955949] NEDD8-AcM-UBE2M:CUL9:RBX1 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-8956031
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-8951664] Neddylation
(precedingEvent)	[Reaction:R-CFA-8956025] AcM-UBE2M transfers NEDD8 to CUL9:RBX1
(inferredTo)	[Reaction:R-HSA-8956031] NEDD8:AcM-UBE2M binds CUL9:RBX1 ubiquitin ligase complex

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