Reactome | Transcriptional Regulation by E2F6

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Transcriptional Regulation by E2F6 Show undefined attributes

created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10331613
displayName	Transcriptional Regulation by E2F6
eventOf	[Pathway:R-CFA-212436] Generic Transcription Pathway - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:396779] negative regulation of G0 to G1 transition
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-CFA-8953111] E2F6 binds TFDP1 - Canis familiaris [Reaction:R-CFA-8954056] E2F6 binds TFDP2 - Canis familiaris [Reaction:R-CFA-8953115] E2F6:TFDP1 binds to MGA:MAX - Canis familiaris [Reaction:R-CFA-8953418] EHMT1:EHMT2 complex binds E2F6.com-1 core - Canis familiaris [Reaction:R-CFA-9007283] CBX3 and PRC1.6 associate with E2F6.com-1 - Canis familiaris [Reaction:R-CFA-8954082] E2F6 binds the PRC1 complex - Canis familiaris [Reaction:R-CFA-8954117] E2F6:TFDP1 binds EPC1 - Canis familiaris [Reaction:R-CFA-8954110] E2F6:TFDP1:EPC1 binds the PRC2 complex - Canis familiaris [Reaction:R-CFA-9007447] E2F6 forms the PRC1L4 complex - Canis familiaris [Reaction:R-CFA-9007539] CHEK1 phosphorylates E2F6 - Canis familiaris
inferredFrom	[Pathway:R-HSA-8953750] Transcriptional Regulation by E2F6 - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Transcriptional Regulation by E2F6
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49646] Canis familiaris
stId	R-CFA-8953750
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-212436] Generic Transcription Pathway
(inferredTo)	[Pathway:R-HSA-8953750] Transcriptional Regulation by E2F6

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