Reactome | FAM20C phosphorylates FAM20C substrates

Schema > Reaction > Entries

FAM20C phosphorylates FAM20C substrates Show undefined attributes

catalystActivity	[CatalystActivity:10314237] protein serine/threonine kinase activity of FAM20C:FAM20C substrates [endoplasmic reticulum lumen]
category	transition
compartment	[Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10314245
displayName	FAM20C phosphorylates FAM20C substrates
eventOf	[Pathway:R-CFA-8957275] Post-translational protein phosphorylation - Canis familiaris [Pathway:R-CFA-381426] Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8952289] FAM20C phosphorylates FAM20C substrates - Homo sapiens
input	105 × [SimpleEntity:R-ALL-8931885] ATP [endoplasmic reticulum lumen] [Complex:R-CFA-8952321] FAM20C:FAM20C substrates [endoplasmic reticulum lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	FAM20C phosphorylates FAM20C substrates
output	105 × [SimpleEntity:R-ALL-8931884] ADP [endoplasmic reticulum lumen] [Complex:R-CFA-8952335] FAM20C:Phosphorylated FAM20C substrates [endoplasmic reticulum lumen]
regulatedBy	[PositiveRegulation:10314246] Positive regulation by 'FAM20C:FAM20A [endoplasmic reticulum lumen]'
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-8952289
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-8957275] Post-translational protein phosphorylation [Pathway:R-CFA-381426] Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
(inferredTo)	[Reaction:R-HSA-8952289] FAM20C phosphorylates FAM20C substrates