Reactome | IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-CFA-8950267] IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-Y-TYK2:STAT1:STAT3 [plasma membrane] - Canis familiaris
consumedByEvent	[BlackBoxEvent:R-CFA-8950518] STAT1, STAT3 bind p-Y611-IL27RA from Interleukin-27:Interleukin-27 receptor complex - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10313328
displayName	IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane]
hasComponent	[Complex:R-CFA-448442] IL27:EBI3 [extracellular region] [Complex:R-CFA-8950642] p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] [Complex:R-CFA-8950563] p-Y611-IL27RA:p-JAK1 [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-8950331] IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] - Homo sapiens
maxDepth	4
name	IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2
producedByEvent	[BlackBoxEvent:R-CFA-8950340] IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation - Canis familiaris
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-8950331
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[BlackBoxEvent:R-CFA-8950518] STAT1, STAT3 bind p-Y611-IL27RA from Interleukin-27:Interleukin-27 receptor complex
(output)	[BlackBoxEvent:R-CFA-8950340] IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation
(hasComponent)	[Complex:R-CFA-8950267] IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-Y-TYK2:STAT1:STAT3 [plasma membrane]
(inferredTo)	[Complex:R-HSA-8950331] IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane]

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