Reactome | EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:p-EPS15:HGS:STAM [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-CFA-8867047] PTPN3 dephosphorylates EPS15 - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10309304
displayName	EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:p-EPS15:HGS:STAM [plasma membrane]
hasComponent	[Complex:R-CFA-182946] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] [EntityWithAccessionedSequence:R-CFA-182952] EPN1 [plasma membrane] [EntityWithAccessionedSequence:R-CFA-182937] EPS15L1 [plasma membrane] [Complex:R-CFA-8867032] p-Eps15:HGS:STAM [cytosol] [SimpleEntity:R-ALL-179856] PI(4,5)P2 [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-8867035] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:p-EPS15:HGS:STAM [plasma membrane] - Homo sapiens
maxDepth	6
name	EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:p-EPS15:HGS:STAM
producedByEvent	[Reaction:R-CFA-8867041] EGFR phosphorylates EPS15 - Canis familiaris
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-8867035
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-CFA-8867047] PTPN3 dephosphorylates EPS15
(output)	[Reaction:R-CFA-8867041] EGFR phosphorylates EPS15
(inferredTo)	[Complex:R-HSA-8867035] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:p-EPS15:HGS:STAM [plasma membrane]

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