Reactome | GRK2, GRK3, GRK5, GRK6 [plasma membrane]

Schema > DefinedSet > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-CFA-8982648] pS-ADRB2:Catecholamine:GRK [plasma membrane] - Canis familiaris [Complex:R-CFA-8982633] ADRB2:Catecholamine:GRK [plasma membrane] - Canis familiaris
consumedByEvent	[Reaction:R-CFA-8982645] GRKs bind ADRB2:Catecholamine - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10307096
displayName	GRK2, GRK3, GRK5, GRK6 [plasma membrane]
hasMember	[EntityWithAccessionedSequence:R-CFA-50270] GRK2 [plasma membrane] - Canis familiaris [EntityWithAccessionedSequence:R-CFA-8852029] GRK3 [plasma membrane] - Canis familiaris [EntityWithAccessionedSequence:R-CFA-416468] GRK5 [plasma membrane] - Canis familiaris [EntityWithAccessionedSequence:R-CFA-8852159] GRK6 [plasma membrane] - Canis familiaris
inDisease	false
inferredFrom	[DefinedSet:R-HSA-8852026] GRK2, GRK3, GRK5, GRK6 [plasma membrane] - Homo sapiens
maxDepth	2
name	GRK2, GRK3, GRK5, GRK6
producedByEvent	[Reaction:R-CFA-8982641] ADRB2:GRK complex dissociates to Phosphorylated ADRB2 - Canis familiaris
schemaClass	DefinedSet
species	[Species:49646] Canis familiaris
stId	R-CFA-8852026

(output)	[Reaction:R-CFA-8982641] ADRB2:GRK complex dissociates to Phosphorylated ADRB2
(activeUnit)	[CatalystActivity:10307104] beta-adrenergic receptor kinase activity of ADRB2:Catecholamine:GRK [plasma membrane]
(hasComponent)	[Complex:R-CFA-8982648] pS-ADRB2:Catecholamine:GRK [plasma membrane] [Complex:R-CFA-8982633] ADRB2:Catecholamine:GRK [plasma membrane]
(input)	[Reaction:R-CFA-8982645] GRKs bind ADRB2:Catecholamine
(inferredTo)	[DefinedSet:R-HSA-8852026] GRK2, GRK3, GRK5, GRK6 [plasma membrane]