Reactome | phospho-p-Y1007-JAK2 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-CFA-6786753] p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] - Canis familiaris [Complex:R-CFA-1169228] p(Y332,487,627)-Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10233489
displayName	phospho-p-Y1007-JAK2 [cytosol]
endCoordinate	1132
hasModifiedResidue	[ModifiedResidue:10233487] O4'-phospho-L-tyrosine at 1007 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-873799] p-Y1007-JAK2 [cytosol] - Homo sapiens
maxDepth	1
memberOf	[DefinedSet:R-CFA-6788568] p-Y1007-JAK2,p-Y-TYK2 [cytosol] - Canis familiaris [CandidateSet:R-CFA-1112596] Activated JAK1, JAK2, TYK2 [cytosol] - Canis familiaris
name	phospho-p-Y1007-JAK2 A0A8I3NVH4
referenceEntity	[ReferenceGeneProduct:uniprot:A0A8I3NVH4] UniProt:A0A8I3NVH4
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:49646] Canis familiaris
stId	R-CFA-873799
startCoordinate	1

(hasComponent)	[Complex:R-CFA-6786753] p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] [Complex:R-CFA-1169228] p(Y332,487,627)-Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] [Complex:R-CFA-1168892] Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] [Complex:R-CFA-1470000] p-JAK2:SFKs:p-KIT complex:p-STATs [plasma membrane] [Complex:R-CFA-1469999] p-JAK2:SFKs:p-KIT complex:p-STAT dimers [plasma membrane] [Complex:R-CFA-1433527] p-JAK2:SFKs:p-KIT complex:STATs [plasma membrane] [Complex:R-CFA-1433552] p-JAK2:SFKs:p-KIT complex [plasma membrane] [Complex:R-CFA-912306] p(Y593)-IL3RB:Activated JAK2 [plasma membrane] [Complex:R-CFA-1364053] Activated PRLR:p(Y1007)-JAK2 [plasma membrane] [Complex:R-CFA-873819] IFNGR2:p-JAK2 [plasma membrane] [Complex:R-CFA-893554] IL3RB:p-Y1007-JAK2 [plasma membrane]
(hasMember)	[DefinedSet:R-CFA-6788568] p-Y1007-JAK2,p-Y-TYK2 [cytosol] [CandidateSet:R-CFA-1112596] Activated JAK1, JAK2, TYK2 [cytosol]
(activeUnit)	[CatalystActivity:10260730] protein tyrosine kinase activity of STAT1 bound to p-IFNGR1 [plasma membrane] [CatalystActivity:10260689] protein tyrosine kinase activity of IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane] [CatalystActivity:10260945] protein tyrosine kinase activity of Tyrosine kinases that phosphorylate the Common beta chain [plasma membrane]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-873799] p-Y1007-JAK2 [cytosol]