Reactome | (d)GMP + ATP <=> (d)GDP + ADP (GUK1)

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(d)GMP + ATP <=> (d)GDP + ADP (GUK1) Show undefined attributes

catalystActivity	[CatalystActivity:10230445] GMP kinase activity of GUK1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10230447
displayName	(d)GMP + ATP <=> (d)GDP + ADP (GUK1)
eventOf	[Pathway:R-CFA-499943] Interconversion of nucleotide di- and triphosphates - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-482619] (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) - Canis familiaris
inferredFrom	[Reaction:R-HSA-73788] (d)GMP + ATP <=> (d)GDP + ADP (GUK1) - Homo sapiens
input	[DefinedSet:R-ALL-500071] (d)GMP [cytosol] [SimpleEntity:R-ALL-113592] ATP [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	(d)GMP + ATP <=> (d)GDP + ADP (GUK1) GMP + ATP => GDP + ADP dGMP + ATP => dGDP + ADP
output	[DefinedSet:R-ALL-500077] (d)GDP [cytosol] [SimpleEntity:R-ALL-29370] ADP [cytosol]
precedingEvent	[Reaction:R-CFA-73792] XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate - Canis familiaris [Reaction:R-CFA-74207] dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-73788
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-499943] Interconversion of nucleotide di- and triphosphates
(precedingEvent)	[Reaction:R-CFA-482619] (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3)
(inferredTo)	[Reaction:R-HSA-73788] (d)GMP + ATP <=> (d)GDP + ADP (GUK1)

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