Reactome | TP53I3 dimerizes

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10302767
displayName	TP53I3 dimerizes
eventOf	[Pathway:R-CFA-6803205] TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-6799722] TP53I3 oxidoreductase generates unstable semiquinones - Canis familiaris
inferredFrom	[Reaction:R-HSA-6799466] TP53I3 dimerizes - Homo sapiens
input	2 × [DefinedSet:R-CFA-6799460-3] Homologues of TP53I3 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	TP53I3 dimerizes
output	[Complex:R-CFA-6799448] TP53I3 Dimer [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-6799466
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-6803205] TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
(precedingEvent)	[Reaction:R-CFA-6799722] TP53I3 oxidoreductase generates unstable semiquinones
(inferredTo)	[Reaction:R-HSA-6799466] TP53I3 dimerizes