Reactome | ALDH7A1 oxidises BETALD to BET

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ALDH7A1 oxidises BETALD to BET Show undefined attributes

catalystActivity	[CatalystActivity:10300310] betaine-aldehyde dehydrogenase (NAD+) activity of ALDH7A1 [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10300312
displayName	ALDH7A1 oxidises BETALD to BET
eventOf	[Pathway:R-CFA-6798163] Choline catabolism - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-6797955] ALDH7A1 oxidises BETALD to BET - Homo sapiens
input	[SimpleEntity:R-ALL-6798194] BETALD [mitochondrial matrix] [SimpleEntity:R-ALL-113521] H2O [mitochondrial matrix] [SimpleEntity:R-ALL-113526] NAD+ [mitochondrial matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	ALDH7A1 oxidises BETALD to BET betaine aldehyde + NAD(+) + H2O => glycine betaine + NADH + 2 H(+)
output	[SimpleEntity:R-ALL-6798202] BET [mitochondrial matrix] 2 × [SimpleEntity:R-ALL-113529] H+ [mitochondrial matrix] [SimpleEntity:R-ALL-29362] NADH [mitochondrial matrix]
precedingEvent	[Reaction:R-CFA-6797961] CHDH oxidises Cho to BETALD - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-6797955
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-6798163] Choline catabolism
(inferredTo)	[Reaction:R-HSA-6797955] ALDH7A1 oxidises BETALD to BET

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