Reactome | Histone H2A is dubiquitinated by the PR-DUB complex

Schema > Reaction > Entries

Histone H2A is dubiquitinated by the PR-DUB complex Show undefined attributes

catalystActivity	[CatalystActivity:10296029] cysteine-type deubiquitinase activity of PR-DUB complex [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10296031
displayName	Histone H2A is dubiquitinated by the PR-DUB complex
eventOf	[Pathway:R-CFA-5689603] UCH proteinases - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5690790] Histone H2A is dubiquitinated by the PR-DUB complex - Homo sapiens
input	[SimpleEntity:R-ALL-113518] H2O [nucleoplasm] [CandidateSet:R-CFA-6782529] Ub-histone H2A [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Histone H2A is dubiquitinated by the PR-DUB complex
output	[CandidateSet:R-CFA-4657028] Histone H2A [nucleoplasm] [DefinedSet:R-CFA-68524] Ub [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-5690790
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-5689603] UCH proteinases
(inferredTo)	[Reaction:R-HSA-5690790] Histone H2A is dubiquitinated by the PR-DUB complex

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