Reactome | POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10291877] DNA-directed DNA polymerase activity of POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-CFA-5655892] POLK incorporates dNMP opposite to damaged DNA base - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10291868
displayName	POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm]
hasComponent	[Complex:R-CFA-5655850] MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] [Complex:R-CFA-5655492] POLK:Mg2+,Mn2+ [nucleoplasm] [Complex:R-CFA-110279] POLZ [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-3006726] REV1 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-5655852] POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] - Homo sapiens
maxDepth	7
name	POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template
producedByEvent	[Reaction:R-CFA-5655835] POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template - Canis familiaris
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-5655852
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-CFA-5655892] POLK incorporates dNMP opposite to damaged DNA base
(physicalEntity)	[CatalystActivity:10291877] DNA-directed DNA polymerase activity of POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm]
(output)	[Reaction:R-CFA-5655835] POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template
(inferredTo)	[Complex:R-HSA-5655852] POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm]

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