Reactome | Activated FGFR1:p-FRS bind to PPTN11

Schema > Reaction > Entries

Activated FGFR1:p-FRS bind to PPTN11 Show undefined attributes

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10291586
displayName	Activated FGFR1:p-FRS bind to PPTN11
eventOf	[Pathway:R-CFA-5654693] FRS-mediated FGFR1 signaling - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-5654587] Activated FGFR1:p-FRS phosphorylates PPTN11 - Canis familiaris
inferredFrom	[Reaction:R-HSA-5654584] Activated FGFR1:p-FRS bind to PPTN11 - Homo sapiens
input	[DefinedSet:R-CFA-5654262] Activated FGFR1:p-FRS [plasma membrane] [EntityWithAccessionedSequence:R-CFA-162563] PTPN11 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Activated FGFR1:p-FRS bind to PPTN11
output	[Complex:R-CFA-5654268] Activated FGFR1:p-FRS:PTPN11 [plasma membrane]
precedingEvent	[Reaction:R-CFA-5654575] Activated FGFR1 phosphorylates FRS2 - Canis familiaris [Reaction:R-CFA-5654578] Activated FGFR1 phosphorylates FRS3 - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-5654584
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-5654693] FRS-mediated FGFR1 signaling
(precedingEvent)	[Reaction:R-CFA-5654587] Activated FGFR1:p-FRS phosphorylates PPTN11
(inferredTo)	[Reaction:R-HSA-5654584] Activated FGFR1:p-FRS bind to PPTN11

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