Reactome | SESN1,2,3 bind AMPK

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10290668
displayName	SESN1,2,3 bind AMPK
eventOf	[Pathway:R-CFA-5628897] TP53 Regulates Metabolic Genes - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5631941] SESN1,2,3 bind AMPK - Homo sapiens
input	[Complex:R-CFA-380931] p-AMPK heterotrimer:AMP [cytosol] [CandidateSet:R-CFA-5629191] SESN1,2,3 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	SESN1,2,3 bind AMPK
output	[Complex:R-CFA-5631939] SESN1,2,3:p-AMPK heterotrimer:AMP [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-5631941
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-5628897] TP53 Regulates Metabolic Genes
(inferredTo)	[Reaction:R-HSA-5631941] SESN1,2,3 bind AMPK

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