Reactome | MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met

Schema > Reaction > Entries

MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met Show undefined attributes

catalystActivity	[CatalystActivity:10288867] methionine adenosyltransferase activity of MAT2B:MAT2A:K+:2Mg2+ [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10288869
displayName	MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met
eventOf	[Pathway:R-CFA-156581] Methylation - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-175987] NNMT transfers CH3 from AdoMet to PY - Canis familiaris [Reaction:R-CFA-158609] TPMT transfers CH3 from AdoMet to 6MP - Canis familiaris [Reaction:R-CFA-175983] COMT transfer CH3 from AdoMet to 3,4DHBNZ - Canis familiaris
inferredFrom	[Reaction:R-HSA-5603114] MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-174390] L-Met [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met AdoMet is sythesized from methionine's reaction with ATP
output	[SimpleEntity:R-ALL-71284] AdoMet [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol] [SimpleEntity:R-ALL-111294] PPi [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-5603114
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-156581] Methylation
(precedingEvent)	[Reaction:R-CFA-175987] NNMT transfers CH3 from AdoMet to PY [Reaction:R-CFA-158609] TPMT transfers CH3 from AdoMet to 6MP [Reaction:R-CFA-175983] COMT transfer CH3 from AdoMet to 3,4DHBNZ
(inferredTo)	[Reaction:R-HSA-5603114] MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met

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