Reactome | OCT1 transports organic cations into hepatic cells

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OCT1 transports organic cations into hepatic cells Show undefined attributes

catalystActivity	[CatalystActivity:10260112] transmembrane transporter activity of OCT1 [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10260114
displayName	OCT1 transports organic cations into hepatic cells
eventOf	[Pathway:R-CFA-549127] SLC-mediated transport of organic cations - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-549129] OCT1 transports organic cations into hepatic cells - Homo sapiens
input	[DefinedSet:R-ALL-549264] OCT1 substrates [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	OCT1 transports organic cations into hepatic cells
output	[DefinedSet:R-ALL-549250] OCT1 substrates [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-549129
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-549127] SLC-mediated transport of organic cations
(inferredTo)	[Reaction:R-HSA-549129] OCT1 transports organic cations into hepatic cells

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