Reactome | MLH1:PMS2 [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-CFA-5358633] EXO1:MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] - Canis familiaris
consumedByEvent	[Reaction:R-CFA-5358510] MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10287849
displayName	MLH1:PMS2 [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-CFA-912495] MLH1 [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-5357527] PMS2 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-5357522] MLH1:PMS2 [nucleoplasm] - Homo sapiens
maxDepth	2
name	MLH1:PMS2
producedByEvent	[Reaction:R-CFA-5444523] Formation of MSH1:PMS2 Complex - Canis familiaris
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-5357522
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(hasComponent)	[Complex:R-CFA-5358633] EXO1:MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] [Complex:R-CFA-5358528] MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] [Complex:R-CFA-5358511] MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch [nucleoplasm]
(input)	[Reaction:R-CFA-5358510] MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA
(output)	[Reaction:R-CFA-5444523] Formation of MSH1:PMS2 Complex
(inferredTo)	[Complex:R-HSA-5357522] MLH1:PMS2 [nucleoplasm]