Reactome | FRAT proteins bind GSK3beta

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10287317
displayName	FRAT proteins bind GSK3beta
eventOf	[Pathway:R-CFA-4641262] Disassembly of the destruction complex and recruitment of AXIN to the membrane - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5323526] FRAT proteins bind GSK3beta - Homo sapiens
input	[DefinedSet:R-CFA-1226058] FRAT1,2 [cytosol] [EntityWithAccessionedSequence:R-CFA-2997551] GSK3B [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	FRAT proteins bind GSK3beta
output	[Complex:R-CFA-1226052] FRAT1,2:GSK3beta [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-5323526
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-4641262] Disassembly of the destruction complex and recruitment of AXIN to the membrane
(inferredTo)	[Reaction:R-HSA-5323526] FRAT proteins bind GSK3beta

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