Reactome | hp-IRAK1,hp-IRAK4 bind Pellino1,2,3

Schema > Reaction > Entries

category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10258799
displayName	hp-IRAK1,hp-IRAK4 bind Pellino1,2,3
eventOf	[Pathway:R-CFA-9020702] Interleukin-1 signaling - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-450690] hp-IRAK1,hp-IRAK4 bind Pellino1,2,3 - Homo sapiens
input	[DefinedSet:R-CFA-450810] p-2S,S376,T,T209,T387-IRAK1, IRAK4 [cytosol] 2 × [DefinedSet:R-CFA-450814] Pellino 1,2,3 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	hp-IRAK1,hp-IRAK4 bind Pellino1,2,3
output	[DefinedSet:R-CFA-451413] hp-IRAK1:Pellino, IRAK4:Pellino [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-450690
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-9020702] Interleukin-1 signaling
(inferredTo)	[Reaction:R-HSA-450690] hp-IRAK1,hp-IRAK4 bind Pellino1,2,3

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