Reactome | IL31:IL31RA:JAK1 binds OSMR:JAK1

Schema > BlackBoxEvent > Entries

category	omitted
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10258135
displayName	IL31:IL31RA:JAK1 binds OSMR:JAK1
eventOf	[Pathway:R-CFA-6788467] IL-6-type cytokine receptor ligand interactions - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-448660] IL31:IL31RA:JAK1 binds OSMR:JAK1 - Homo sapiens
input	[Complex:R-CFA-8983441] IL31:IL31RA:JAK1 [plasma membrane] [Complex:R-CFA-8983748] OSMR:JAK1 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	IL31:IL31RA:JAK1 binds OSMR:JAK1
output	[Complex:R-CFA-448565] IL31:IL31RA:JAK1:OSMR:JAK1 [plasma membrane]
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:49646] Canis familiaris
stId	R-CFA-448660
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-6788467] IL-6-type cytokine receptor ligand interactions
(inferredTo)	[BlackBoxEvent:R-HSA-448660] IL31:IL31RA:JAK1 binds OSMR:JAK1

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