Reactome | Interleukin-23 binds interleukin-23 receptor

Schema > BlackBoxEvent > Entries

Interleukin-23 binds interleukin-23 receptor Show undefined attributes

category	omitted
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10258013
displayName	Interleukin-23 binds interleukin-23 receptor
eventOf	[Pathway:R-CFA-9020933] Interleukin-23 signaling - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-447130] Interleukin-23 binds interleukin-23 receptor - Homo sapiens
input	[Complex:R-CFA-447217] IL12B:IL23A [extracellular region] [Complex:R-CFA-8950046] IL12RB1:TYK2 [plasma membrane] [Complex:R-CFA-8950151] IL23R:JAK2 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Interleukin-23 binds interleukin-23 receptor
output	[Complex:R-CFA-447186] IL23A:IL12B:IL23R:JAK2:IL12RB1:TYK2 [plasma membrane]
precedingEvent	[BlackBoxEvent:R-CFA-8950741] IL12B:IL23A translocates from ER lumen to extracellular space - Canis familiaris
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:49646] Canis familiaris
stId	R-CFA-447130
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-9020933] Interleukin-23 signaling
(inferredTo)	[BlackBoxEvent:R-HSA-447130] Interleukin-23 binds interleukin-23 receptor

Cite Us!