Reactome | PECAM1 is phosphorylated

Schema > BlackBoxEvent > Entries

PECAM1 is phosphorylated Show undefined attributes

category	omitted
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10256997
displayName	PECAM1 is phosphorylated
eventOf	[Pathway:R-CFA-432142] Platelet sensitization by LDL - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-432143] PECAM-1 binds PP2A - Canis familiaris [Reaction:R-CFA-210277] Interaction of PECAM-1 and SHP-1 - Canis familiaris [Reaction:R-CFA-210294] Interaction of PECAM-1 and SHP-2 - Canis familiaris
inferredFrom	[BlackBoxEvent:R-HSA-435244] PECAM1 is phosphorylated - Homo sapiens
input	2 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [EntityWithAccessionedSequence:R-CFA-114686] PECAM1 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	PECAM1 is phosphorylated
output	2 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [EntityWithAccessionedSequence:R-CFA-210007] phospho-PECAM1 [plasma membrane]
regulatedBy	[PositiveRegulation:10256998] Positive regulation by 'LDL [extracellular region]'
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:49646] Canis familiaris
stId	R-CFA-435244
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-432142] Platelet sensitization by LDL
(precedingEvent)	[Reaction:R-CFA-432143] PECAM-1 binds PP2A [Reaction:R-CFA-210277] Interaction of PECAM-1 and SHP-1 [Reaction:R-CFA-210294] Interaction of PECAM-1 and SHP-2
(inferredTo)	[BlackBoxEvent:R-HSA-435244] PECAM1 is phosphorylated