Reactome | Gbeta:gamma recruits PI3K gamma

Schema > Reaction > Entries

Gbeta:gamma recruits PI3K gamma Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10253606
displayName	Gbeta:gamma recruits PI3K gamma
eventOf	[Pathway:R-CFA-392451] G beta:gamma signalling through PI3Kgamma - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-392300] G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 - Canis familiaris
inferredFrom	[Reaction:R-HSA-392295] Gbeta:gamma recruits PI3K gamma - Homo sapiens
input	[Complex:R-CFA-167434] G-protein beta-gamma complex [plasma membrane] [Complex:R-CFA-392291] PI3K gamma [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Gbeta:gamma recruits PI3K gamma
output	[Complex:R-CFA-392293] G-protein beta-gamma:PI3K gamma [plasma membrane]
precedingEvent	[Reaction:R-CFA-392202] Dissociation of the P2Y purinoceptor 12:Gi complex - Canis familiaris [Reaction:R-CFA-418576] Dissociation of the P2Y purinoceptor 1:Gq complex - Canis familiaris [Reaction:R-CFA-397891] Thrombin-activated PARs:G12/13 (active) dissociate - Canis familiaris [Reaction:R-CFA-397835] Thrombin-activated PARs:Gq (active) dissociate - Canis familiaris [Reaction:R-CFA-751019] The Ligand:GPCR:G12/13 complex dissociates - Canis familiaris [Reaction:R-CFA-749454] The Ligand:GPCR:Gi complex dissociates - Canis familiaris [Reaction:R-CFA-749452] The Ligand:GPCR:Gq complex dissociates - Canis familiaris [Reaction:R-CFA-751024] The Ligand:GPCR:Gz complex dissociates - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-392295
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-392451] G beta:gamma signalling through PI3Kgamma
(precedingEvent)	[Reaction:R-CFA-392300] G beta:gamma activated PI3Kgamma converts PIP2 to PIP3
(inferredTo)	[Reaction:R-HSA-392295] Gbeta:gamma recruits PI3K gamma