Reactome | EDNRA,EDNRB bind EDNs

Schema > Reaction > Entries

EDNRA,EDNRB bind EDNs Show undefined attributes

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10252643
displayName	EDNRA,EDNRB bind EDNs
eventOf	[Pathway:R-CFA-375276] Peptide ligand-binding receptors - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-388560] EDNRA,EDNRB bind EDNs - Homo sapiens
input	[DefinedSet:R-CFA-388547] EDNRA,EDNRB [plasma membrane] [DefinedSet:R-CFA-388544] EDNs [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	EDNRA,EDNRB bind EDNs Endothelin receptors bind endothelin
output	[Complex:R-CFA-388546] EDNRA,EDNRB:EDNs [plasma membrane]
precedingEvent	[Reaction:R-CFA-8876868] ECE1 cleaves EDN1(53-90) - Canis familiaris [Reaction:R-CFA-5694082] XK:KEL:Zn2+ cleaves EDN3 - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-388560
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-375276] Peptide ligand-binding receptors
(inferredTo)	[Reaction:R-HSA-388560] EDNRA,EDNRB bind EDNs

Cite Us!